Ahmed’s primary research focus is aimed at understanding the role of epigenetic, posttranslational, and cell signaling mechanisms orchestrated by a network of cytokines and chemokines in autoimmune and chronic inflammatory diseases, including rheumatoid arthritis (RA), osteoarthritis (OA), and gout. His current research focus is to examine the role of epigenetic and posttranslational mechanisms involved in tissue damage and inflammation induced by pro-inflammatory cytokines such as IL-6, IL-1β, and TNF-α in RA and other autoimmune diseases. Ahmed’s research lab is currently one of the active groups involved in developing novel targeted therapeutics (microRNA and small-molecule inhibitors) in the prevention and treatment of RA, gout, OA, and vascular inflammation.
Ahmed’s research is currently funded by grants from the National Institutes of Health, the Rheumatology Research Foundation.
Recent Research Support
07/12/18-06/30/2023 | “MicroRNA-based therapy for rheumatoid arthritis.”
NIAMS/NIH R01 AR063104
Principal Investigator: Salah-uddin Ahmed
08/16/19-08/15/21 | “Elucidating the Role of Sulfatase-2 in RA Pathogenesis.”
NIAMS/NIH F31 AR076204
Principal Investigator: Ruby J Siegel; Mentor: Salah-uddin Ahmed
07/01/20-06/30/21 | “Role of guanylate binding proteins in gouty arthritis.”
Rheumatology Research Foundation Medical and Graduate Student Preceptorship
Principal Investigator (Mentor): Salah-uddin Ahmed