Eric

Butz

PhD

Education & Training: 

BA, Carleton College, Northfield, MN (1983)

PhD in Microbiology, University of Minnesota, Minneapolis, MN (1994)

Postdoctoral Fellow- Michael Bevan Lab, University of Washington, Seattle, WA (1994-1998)

Honors: 

Amgen Development Hall of Fame (2003)

Amgen Development Hall of Fame (2004)

PubMed: 

PubMed Bibliography

Publications: 

Selected-

Goldrath AW, Sivakumar PV, Glaccum M, Kennedy MK, Bevan MJ, Benoist C, Mathis D, Butz EA. Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ Tcells. Journal of Experimental Medicine. 195(12):1515-22, 2002   

Daro E, Butz E, Smith J, Teepe M, Maliszewski CR, McKenna HJ. Comparison of the functional properties of murine dendritic cells generated in vivo with Flt3 ligand, GM-CSF and Flt3 ligand
plus GM-CSF. Cytokine. 17(3):119-30, 2002  

V. Dolfi, DV, C. Boesteanu, AC, Petrovas, C, Xia, D, Butz, EA, and Katsikis, PD. Late Signals from CD27 Prevent Fas-Dependent Apoptosis of Primary CD8+ T Cells J. Immunol., 180: 2912–21, 2008 

Malamut G, El Machhour R, Montcuquet N, Martin-Lanneree S, Dusanter-Fourt I, Verkarre V, Mention JJ, Rahmi G, Kiyono H, Butz EA, Brousse N, Cellier C, Cerf-Bensussan N, Meresse B. IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesis. Journal of Clinical Investigation. 120(6):2131-43, 2010  

Liu RB, Engels B, Arina A, Schreiber K, Hyjek E, Schietinger A, Binder DC, Butz E, Krausz T, Rowley DA, Jabri B, Schreiber H, Densely granulated murine NK cells eradicate large solid tumors. Cancer Research. 72(8):1964-74, 2012

Lebrec H, Horner MJ, Gorski KS, Tsuji W, Xia D, Pan WJ, Means G, Pietz G, Li N, Retter M, Shaffer K, Patel N, Narayanan PK, Butz EA, Homeostasis of human NK cells is not IL-15 dependent. Journal of Immunology. 191(11):5551-8, 2013 

 Pan WJ, Li H, Xiao JJ, Horner MJ, Lebrec HN, Butz EA, Kaliyaperumal A, Cheah TC, Ortiz RC,Prokop SP, Buntich SA, Boren BM, Wolford ST, Tsuji WH, Wienkers LC, Köck K, Modeling the pharmacokinetic-pharmacodynamic relationship of the monoclonal anti-macaque-IL-15 antibody Hu714MuXHu in cynomolgus monkeys. Pharmacology Research & Perspectives 3(6):e00199, 2015